naproxen related substance tlc analysis

What is the most important information I should know about naproxen?
• Take naproxen with food, milk, or an antacid to lessen stomach upset naproxen related substance tlc analysis.
• Do not crush or chew any extended-release forms of naproxen naproxen related substance tlc analysis. Swallowthem whole naproxen related substance tlc analysis. They are specially formulated to release slowly in your body naproxen related substance tlc analysis. Askyour pharmacist if you do not know if you have an extended-release formulation naproxen related substance tlc analysis.
• Watch for bloody, black, or tarry stools or blood in your vomit naproxen related substance tlc analysis. Thesesymptoms could indicate damage to your gastrointestinal tract naproxen related substance tlc analysis.
• If you drink more than three alcoholic beverages a day, naproxen mayincrease the risk of stomach bleeding naproxen related substance tlc analysis.
• Use caution when driving, operating machinery, or performing other hazardousactivities naproxen related substance tlc analysis. Naproxen may cause dizziness naproxen related substance tlc analysis. If you experience dizziness, avoidthese activities naproxen related substance tlc analysis.

What is naproxen?
• Naproxen is in a class of drugs called nonsteroidal anti-inflammatorydrugs (NSAIDs) naproxen related substance tlc analysis.
• Naproxen works by reducing hormones that cause inflammation and painin the body naproxen related substance tlc analysis. Naproxen is used to reduce pain, inflammation, and stiffness causedby many conditions, such as osteoarthritis, rheumatoid arthritis, gout, ankylosingspondylitis, injury, abdominal cramps associated with menstruation, tendinitis,and bursitis naproxen related substance tlc analysis.
• Naproxen may also be used for purposes other than those listed in thismedication guide naproxen related substance tlc analysis.

Who should not take naproxen?
• Before taking this medication, tell your doctor if you
· have an allergy to aspirin or any other NSAIDs,
· have an ulcer or bleeding in your stomach,
· drink more than three alcoholic beverages a day,
· have liver disease,
· have kidney disease,
· have a coagulation (bleeding) disorder,
· have congestive heart failure,
· have fluid retention,
· have heart disease, or
· have high blood pressure naproxen related substance tlc analysis.
• You may not be able to take naproxen, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove naproxen related substance tlc analysis.
• Naproxen is in the FDA pregnancy category B naproxen related substance tlc analysis. This means that it is unlikelyto harm an unborn baby naproxen related substance tlc analysis. Naproxen should not be taken late in pregnancy (thethird trimester) because a similar drug is known to affect the baby's heart naproxen related substance tlc analysis. Do not take naproxen without first talking to your doctor if you are pregnant naproxen related substance tlc analysis.
• Naproxen passes into breast milk and may harm a nursing infant naproxen related substance tlc analysis. Do nottake this medicine without first talking to your doctor if you are breast-feedinga baby naproxen related substance tlc analysis.

How should I take naproxen?
• Take naproxen exactly as directed by your doctor naproxen related substance tlc analysis. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou naproxen related substance tlc analysis.
• Take each dose with a full glass of water naproxen related substance tlc analysis.
• Take naproxen with milk, food, or an antacid to lessen stomach upset naproxen related substance tlc analysis.
• Do not crush or chew any extended-release forms of naproxen naproxen related substance tlc analysis. Swallowthem whole naproxen related substance tlc analysis. These are specially formulated to release slowly in your body naproxen related substance tlc analysis. Askyour pharmacist if you do not know if you have an extended release formulation naproxen related substance tlc analysis.
• To ensure that you get a correct dose, measure the liquid form of naproxenwith a special dose-measuring spoon or cup, not with a regular tablespoon naproxen related substance tlc analysis. Ifyou do not have a dose-measuring device, ask your pharmacist where you can getone naproxen related substance tlc analysis. Shake the suspension well
• Store naproxen at room temperature away from moisture and heat naproxen related substance tlc analysis.

What happens if I miss a dose?
• Take the missed dose as soon as you remember up to 2 hours late naproxen related substance tlc analysis. If morethan 2 hours have passed since the missed dose, skip it and take only your nextregularly scheduled dose naproxen related substance tlc analysis. Do not take a double dose naproxen related substance tlc analysis.

What happens if I overdose?
• Seek emergency medical attention naproxen related substance tlc analysis.
• Symptoms of a naproxen overdose include nausea, vomiting, stomach pain,dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures,sweating, numbness or tingling, little or no urine production, and slow breathing naproxen related substance tlc analysis.

What should I avoid while taking naproxen?
• Avoid prolonged exposure to sunlight naproxen related substance tlc analysis. Naproxen may increase the sensitivityof your skin to sunlight naproxen related substance tlc analysis. Use a sunscreen and wear protective clothing whenexposure to the sun is unavoidable naproxen related substance tlc analysis.
• Use caution when driving, operating machinery, or performing other hazardousactivities naproxen related substance tlc analysis. Naproxen may cause dizziness naproxen related substance tlc analysis. If you experience dizziness, avoidthese activities naproxen related substance tlc analysis.
• If you drink more than three alcoholic beverages a day, naproxen mayincrease the risk of stomach bleeding naproxen related substance tlc analysis.

What are the possible side effects of naproxen?
• If you experience any of the following serious side effects, stop takingnaproxen and seek medical treatment or call your doctor immediately:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· muscle cramps, numbness, or tingling;
· ulcers (open sores) in the mouth;
· rapid weight gain (fluid retention);
· seizures;
· black, bloody, or tarry stools;
· blood in your urine or vomit;
· decreased hearing or ringing in the ears;
· yellowing of your skin or eyes (jaundice); or
· abdominal cramping, heartburn, or indigestion naproxen related substance tlc analysis.
• Other, less serious side effects may be more likely to occur naproxen related substance tlc analysis. Continueto take naproxen and talk to your doctor if you experience
· dizziness or headache;
· nausea, gaseousness, diarrhea, or constipation;
· depression;
· fatigue or weakness;
· dry mouth; or
· irregular menstrual periods naproxen related substance tlc analysis.
• Side effects other than those listed here may also occur naproxen related substance tlc analysis. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome naproxen related substance tlc analysis.

What other drugs will affect naproxen?
• Other prescription and over-the-counter drugs may increase the effectsof naproxen and cause dangerous side effects naproxen related substance tlc analysis. Tell your doctor if you are takingany of the following drugs:
· other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen(Motrin, Rufen, others), ketoprofen (Orudis, Orudis KT, Oruvail);
· other commonly used NSAIDs, including diclofenac (Voltaren, Cataflam),etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin(Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam(Feldene), sulindac (Clinoril), or tolmetin (Tolectin);
· aspirin and other salicylates (forms of aspirin) such as salsalate(Disalcid), choline salicylate, and magnesium salicylate (watch the aspirincontent of other over-the-counter products such as cough, cold, and allergymedicines);
· diuretics (water pills) such as hydrochlorothiazide (HCTZ, Hydrodiuril,others), chlorothiazide (Diuril, others), chlorthalidone (Thalitone), bumetanide(Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), spironolactone (Aldactone),and amiloride (Midamor);
· anticoagulants such as warfarin (Coumadin);
· steroids such as prednisone (Deltasone);
· alcohol;
· oral antidiabetic drugs such as glipizide (Glucotrol) and glyburide(Micronase, Diabeta);
· lithium (Eskalith, Lithobid, others);
· cyclosporine (Sandimmune, Neoral); or
· bismuth subsalicylate in drugs such as Pepto-Bismol naproxen related substance tlc analysis.
• Naproxen can also decrease the effects of other drugs, such as
· angiotensin-converting-enzyme (ACE) inhibitors, used to treat highblood pressure and other conditions, such as benazepril (Lotensin) and captopril(Capoten);
· other commonly used ACE inhibitors, including enalapril (Vasotec),fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc),quinapril (Accupril), and ramipril (Altace); and
· beta-blockers, used to treat high blood pressure and other conditions,such as acebutolol (Sectral), metoprolol (Lopressor), propranolol (Inderal),atenolol (Tenormin), and carteolol (Cartrol) naproxen related substance tlc analysis.
• Talk to your doctor before taking naproxen if you are taking any of themedicines listed above naproxen related substance tlc analysis.
• Drugs other than those listed here may also interact with naproxen naproxen related substance tlc analysis. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines naproxen related substance tlc analysis.

Where can I get more information?
• Your pharmacist has additional information about naproxen written forhealth professionals that you may read naproxen related substance tlc analysis.

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