naproxen metabolism
(na PROX en)
Aleve, Aleve Caplet, Anaprox, Anaprox-DS, EC Naprosyn, Naprelan, Naprosyn
What is the most important information I should know about naproxen?
• Take naproxen with food, milk, or an antacid to lessen stomach upset naproxen metabolism.
• Do not crush or chew any extended-release forms of naproxen naproxen metabolism. Swallowthem whole naproxen metabolism. They are specially formulated to release slowly in your body naproxen metabolism. Askyour pharmacist if you do not know if you have an extended-release formulation naproxen metabolism.
• Watch for bloody, black, or tarry stools or blood in your vomit naproxen metabolism. Thesesymptoms could indicate damage to your gastrointestinal tract naproxen metabolism.
• If you drink more than three alcoholic beverages a day, naproxen mayincrease the risk of stomach bleeding naproxen metabolism.
• Use caution when driving, operating machinery, or performing other hazardousactivities naproxen metabolism. Naproxen may cause dizziness naproxen metabolism. If you experience dizziness, avoidthese activities naproxen metabolism.
What is naproxen?
• Naproxen is in a class of drugs called nonsteroidal anti-inflammatorydrugs (NSAIDs) naproxen metabolism.
• Naproxen works by reducing hormones that cause inflammation and painin the body naproxen metabolism. Naproxen is used to reduce pain, inflammation, and stiffness causedby many conditions, such as osteoarthritis, rheumatoid arthritis, gout, ankylosingspondylitis, injury, abdominal cramps associated with menstruation, tendinitis,and bursitis naproxen metabolism.
• Naproxen may also be used for purposes other than those listed in thismedication guide naproxen metabolism.
Who should not take naproxen?
• Before taking this medication, tell your doctor if you
· have an allergy to aspirin or any other NSAIDs,
· have an ulcer or bleeding in your stomach,
· drink more than three alcoholic beverages a day,
· have liver disease,
· have kidney disease,
· have a coagulation (bleeding) disorder,
· have congestive heart failure,
· have fluid retention,
· have heart disease, or
· have high blood pressure naproxen metabolism.
• You may not be able to take naproxen, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove naproxen metabolism.
• Naproxen is in the FDA pregnancy category B naproxen metabolism. This means that it is unlikelyto harm an unborn baby naproxen metabolism. Naproxen should not be taken late in pregnancy (thethird trimester) because a similar drug is known to affect the baby's heart naproxen metabolism. Do not take naproxen without first talking to your doctor if you are pregnant naproxen metabolism.
• Naproxen passes into breast milk and may harm a nursing infant naproxen metabolism. Do nottake this medicine without first talking to your doctor if you are breast-feedinga baby naproxen metabolism.
How should I take naproxen?
• Take naproxen exactly as directed by your doctor naproxen metabolism. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou naproxen metabolism.
• Take each dose with a full glass of water naproxen metabolism.
• Take naproxen with milk, food, or an antacid to lessen stomach upset naproxen metabolism.
• Do not crush or chew any extended-release forms of naproxen naproxen metabolism. Swallowthem whole naproxen metabolism. These are specially formulated to release slowly in your body naproxen metabolism. Askyour pharmacist if you do not know if you have an extended release formulation naproxen metabolism.
• To ensure that you get a correct dose, measure the liquid form of naproxenwith a special dose-measuring spoon or cup, not with a regular tablespoon naproxen metabolism. Ifyou do not have a dose-measuring device, ask your pharmacist where you can getone naproxen metabolism. Shake the suspension well
• Store naproxen at room temperature away from moisture and heat naproxen metabolism.
What happens if I miss a dose?
• Take the missed dose as soon as you remember up to 2 hours late naproxen metabolism. If morethan 2 hours have passed since the missed dose, skip it and take only your nextregularly scheduled dose naproxen metabolism. Do not take a double dose naproxen metabolism.
What happens if I overdose?
• Seek emergency medical attention naproxen metabolism.
• Symptoms of a naproxen overdose include nausea, vomiting, stomach pain,dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures,sweating, numbness or tingling, little or no urine production, and slow breathing naproxen metabolism.
What should I avoid while taking naproxen?
• Avoid prolonged exposure to sunlight naproxen metabolism. Naproxen may increase the sensitivityof your skin to sunlight naproxen metabolism. Use a sunscreen and wear protective clothing whenexposure to the sun is unavoidable naproxen metabolism.
• Use caution when driving, operating machinery, or performing other hazardousactivities naproxen metabolism. Naproxen may cause dizziness naproxen metabolism. If you experience dizziness, avoidthese activities naproxen metabolism.
• If you drink more than three alcoholic beverages a day, naproxen mayincrease the risk of stomach bleeding naproxen metabolism.
What are the possible side effects of naproxen?
• If you experience any of the following serious side effects, stop takingnaproxen and seek medical treatment or call your doctor immediately:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· muscle cramps, numbness, or tingling;
· ulcers (open sores) in the mouth;
· rapid weight gain (fluid retention);
· seizures;
· black, bloody, or tarry stools;
· blood in your urine or vomit;
· decreased hearing or ringing in the ears;
· yellowing of your skin or eyes (jaundice); or
· abdominal cramping, heartburn, or indigestion naproxen metabolism.
• Other, less serious side effects may be more likely to occur naproxen metabolism. Continueto take naproxen and talk to your doctor if you experience
· dizziness or headache;
· nausea, gaseousness, diarrhea, or constipation;
· depression;
· fatigue or weakness;
· dry mouth; or
· irregular menstrual periods naproxen metabolism.
• Side effects other than those listed here may also occur naproxen metabolism. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome naproxen metabolism.
What other drugs will affect naproxen?
• Other prescription and over-the-counter drugs may increase the effectsof naproxen and cause dangerous side effects naproxen metabolism. Tell your doctor if you are takingany of the following drugs:
· other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen(Motrin, Rufen, others), ketoprofen (Orudis, Orudis KT, Oruvail);
· other commonly used NSAIDs, including diclofenac (Voltaren, Cataflam),etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin(Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam(Feldene), sulindac (Clinoril), or tolmetin (Tolectin);
· aspirin and other salicylates (forms of aspirin) such as salsalate(Disalcid), choline salicylate, and magnesium salicylate (watch the aspirincontent of other over-the-counter products such as cough, cold, and allergymedicines);
· diuretics (water pills) such as hydrochlorothiazide (HCTZ, Hydrodiuril,others), chlorothiazide (Diuril, others), chlorthalidone (Thalitone), bumetanide(Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), spironolactone (Aldactone),and amiloride (Midamor);
· anticoagulants such as warfarin (Coumadin);
· steroids such as prednisone (Deltasone);
· alcohol;
· oral antidiabetic drugs such as glipizide (Glucotrol) and glyburide(Micronase, Diabeta);
· lithium (Eskalith, Lithobid, others);
· cyclosporine (Sandimmune, Neoral); or
· bismuth subsalicylate in drugs such as Pepto-Bismol naproxen metabolism.
• Naproxen can also decrease the effects of other drugs, such as
· angiotensin-converting-enzyme (ACE) inhibitors, used to treat highblood pressure and other conditions, such as benazepril (Lotensin) and captopril(Capoten);
· other commonly used ACE inhibitors, including enalapril (Vasotec),fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc),quinapril (Accupril), and ramipril (Altace); and
· beta-blockers, used to treat high blood pressure and other conditions,such as acebutolol (Sectral), metoprolol (Lopressor), propranolol (Inderal),atenolol (Tenormin), and carteolol (Cartrol) naproxen metabolism.
• Talk to your doctor before taking naproxen if you are taking any of themedicines listed above naproxen metabolism.
• Drugs other than those listed here may also interact with naproxen naproxen metabolism. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines naproxen metabolism.
Where can I get more information?
• Your pharmacist has additional information about naproxen written forhealth professionals that you may read naproxen metabolism.
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