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difference between naproxen and naproxen sodium
(na PROX en)
Aleve, Aleve Caplet, Anaprox, Anaprox-DS, EC Naprosyn, Naprelan, Naprosyn

What is the most important information I should know about naproxen?
• Take naproxen with food, milk, or an antacid to lessen stomach upset difference between naproxen and naproxen sodium.
• Do not crush or chew any extended-release forms of naproxen difference between naproxen and naproxen sodium. Swallowthem whole difference between naproxen and naproxen sodium. They are specially formulated to release slowly in your body difference between naproxen and naproxen sodium. Askyour pharmacist if you do not know if you have an extended-release formulation difference between naproxen and naproxen sodium.
• Watch for bloody, black, or tarry stools or blood in your vomit difference between naproxen and naproxen sodium. Thesesymptoms could indicate damage to your gastrointestinal tract difference between naproxen and naproxen sodium.
• If you drink more than three alcoholic beverages a day, naproxen mayincrease the risk of stomach bleeding difference between naproxen and naproxen sodium.
• Use caution when driving, operating machinery, or performing other hazardousactivities difference between naproxen and naproxen sodium. Naproxen may cause dizziness difference between naproxen and naproxen sodium. If you experience dizziness, avoidthese activities difference between naproxen and naproxen sodium.


What is naproxen?
• Naproxen is in a class of drugs called nonsteroidal anti-inflammatorydrugs (NSAIDs) difference between naproxen and naproxen sodium.
• Naproxen works by reducing hormones that cause inflammation and painin the body difference between naproxen and naproxen sodium. Naproxen is used to reduce pain, inflammation, and stiffness causedby many conditions, such as osteoarthritis, rheumatoid arthritis, gout, ankylosingspondylitis, injury, abdominal cramps associated with menstruation, tendinitis,and bursitis difference between naproxen and naproxen sodium.
• Naproxen may also be used for purposes other than those listed in thismedication guide difference between naproxen and naproxen sodium.


Who should not take naproxen?
• Before taking this medication, tell your doctor if you
· have an allergy to aspirin or any other NSAIDs,
· have an ulcer or bleeding in your stomach,
· drink more than three alcoholic beverages a day,
· have liver disease,
· have kidney disease,
· have a coagulation (bleeding) disorder,
· have congestive heart failure,
· have fluid retention,
· have heart disease, or
· have high blood pressure difference between naproxen and naproxen sodium.
• You may not be able to take naproxen, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove difference between naproxen and naproxen sodium.
• Naproxen is in the FDA pregnancy category B difference between naproxen and naproxen sodium. This means that it is unlikelyto harm an unborn baby difference between naproxen and naproxen sodium. Naproxen should not be taken late in pregnancy (thethird trimester) because a similar drug is known to affect the baby's heart difference between naproxen and naproxen sodium. Do not take naproxen without first talking to your doctor if you are pregnant difference between naproxen and naproxen sodium.
• Naproxen passes into breast milk and may harm a nursing infant difference between naproxen and naproxen sodium. Do nottake this medicine without first talking to your doctor if you are breast-feedinga baby difference between naproxen and naproxen sodium.


How should I take naproxen?
• Take naproxen exactly as directed by your doctor difference between naproxen and naproxen sodium. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou difference between naproxen and naproxen sodium.
• Take each dose with a full glass of water difference between naproxen and naproxen sodium.
• Take naproxen with milk, food, or an antacid to lessen stomach upset difference between naproxen and naproxen sodium.
• Do not crush or chew any extended-release forms of naproxen difference between naproxen and naproxen sodium. Swallowthem whole difference between naproxen and naproxen sodium. These are specially formulated to release slowly in your body difference between naproxen and naproxen sodium. Askyour pharmacist if you do not know if you have an extended release formulation difference between naproxen and naproxen sodium.
• To ensure that you get a correct dose, measure the liquid form of naproxenwith a special dose-measuring spoon or cup, not with a regular tablespoon difference between naproxen and naproxen sodium. Ifyou do not have a dose-measuring device, ask your pharmacist where you can getone difference between naproxen and naproxen sodium. Shake the suspension well
• Store naproxen at room temperature away from moisture and heat difference between naproxen and naproxen sodium.


What happens if I miss a dose?
• Take the missed dose as soon as you remember up to 2 hours late difference between naproxen and naproxen sodium. If morethan 2 hours have passed since the missed dose, skip it and take only your nextregularly scheduled dose difference between naproxen and naproxen sodium. Do not take a double dose difference between naproxen and naproxen sodium.


What happens if I overdose?
• Seek emergency medical attention difference between naproxen and naproxen sodium.
• Symptoms of a naproxen overdose include nausea, vomiting, stomach pain,dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures,sweating, numbness or tingling, little or no urine production, and slow breathing difference between naproxen and naproxen sodium.


What should I avoid while taking naproxen?
• Avoid prolonged exposure to sunlight difference between naproxen and naproxen sodium. Naproxen may increase the sensitivityof your skin to sunlight difference between naproxen and naproxen sodium. Use a sunscreen and wear protective clothing whenexposure to the sun is unavoidable difference between naproxen and naproxen sodium.
• Use caution when driving, operating machinery, or performing other hazardousactivities difference between naproxen and naproxen sodium. Naproxen may cause dizziness difference between naproxen and naproxen sodium. If you experience dizziness, avoidthese activities difference between naproxen and naproxen sodium.
• If you drink more than three alcoholic beverages a day, naproxen mayincrease the risk of stomach bleeding difference between naproxen and naproxen sodium.


What are the possible side effects of naproxen?
• If you experience any of the following serious side effects, stop takingnaproxen and seek medical treatment or call your doctor immediately:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· muscle cramps, numbness, or tingling;
· ulcers (open sores) in the mouth;
· rapid weight gain (fluid retention);
· seizures;
· black, bloody, or tarry stools;
· blood in your urine or vomit;
· decreased hearing or ringing in the ears;
· yellowing of your skin or eyes (jaundice); or
· abdominal cramping, heartburn, or indigestion difference between naproxen and naproxen sodium.
• Other, less serious side effects may be more likely to occur difference between naproxen and naproxen sodium. Continueto take naproxen and talk to your doctor if you experience
· dizziness or headache;
· nausea, gaseousness, diarrhea, or constipation;
· depression;
· fatigue or weakness;
· dry mouth; or
· irregular menstrual periods difference between naproxen and naproxen sodium.
• Side effects other than those listed here may also occur difference between naproxen and naproxen sodium. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome difference between naproxen and naproxen sodium.


What other drugs will affect naproxen?
• Other prescription and over-the-counter drugs may increase the effectsof naproxen and cause dangerous side effects difference between naproxen and naproxen sodium. Tell your doctor if you are takingany of the following drugs:
· other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen(Motrin, Rufen, others), ketoprofen (Orudis, Orudis KT, Oruvail);
· other commonly used NSAIDs, including diclofenac (Voltaren, Cataflam),etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin(Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam(Feldene), sulindac (Clinoril), or tolmetin (Tolectin);
· aspirin and other salicylates (forms of aspirin) such as salsalate(Disalcid), choline salicylate, and magnesium salicylate (watch the aspirincontent of other over-the-counter products such as cough, cold, and allergymedicines);
· diuretics (water pills) such as hydrochlorothiazide (HCTZ, Hydrodiuril,others), chlorothiazide (Diuril, others), chlorthalidone (Thalitone), bumetanide(Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), spironolactone (Aldactone),and amiloride (Midamor);
· anticoagulants such as warfarin (Coumadin);
· steroids such as prednisone (Deltasone);
· alcohol;
· oral antidiabetic drugs such as glipizide (Glucotrol) and glyburide(Micronase, Diabeta);
· lithium (Eskalith, Lithobid, others);
· cyclosporine (Sandimmune, Neoral); or
· bismuth subsalicylate in drugs such as Pepto-Bismol difference between naproxen and naproxen sodium.
• Naproxen can also decrease the effects of other drugs, such as
· angiotensin-converting-enzyme (ACE) inhibitors, used to treat highblood pressure and other conditions, such as benazepril (Lotensin) and captopril(Capoten);
· other commonly used ACE inhibitors, including enalapril (Vasotec),fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc),quinapril (Accupril), and ramipril (Altace); and
· beta-blockers, used to treat high blood pressure and other conditions,such as acebutolol (Sectral), metoprolol (Lopressor), propranolol (Inderal),atenolol (Tenormin), and carteolol (Cartrol) difference between naproxen and naproxen sodium.
• Talk to your doctor before taking naproxen if you are taking any of themedicines listed above difference between naproxen and naproxen sodium.
• Drugs other than those listed here may also interact with naproxen difference between naproxen and naproxen sodium. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines difference between naproxen and naproxen sodium.


Where can I get more information?
• Your pharmacist has additional information about naproxen written forhealth professionals that you may read difference between naproxen and naproxen sodium.


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