|
|
|||
|
|||
|
|
|||
|
medication namenda |
|||
|
|
|||
|
|||
 
|
|||
|
|
|||
|
medication namenda Generic Name: memantine HCl Date of Approval: Manufacturer: Treatment for: The U.S medication namenda. Food and Drug Administration (FDA) has approved Namenda (memantineHCl) for the treatment of moderate to severe Alzheimer's disease medication namenda. Namenda isthe first NMDA receptor antagonist to be approved for Alzheimer's disease andis also the only therapy approved for the treatment of moderate to severe Alzheimer'sdisease. Namenda's FDA approval is based on the Agency's review of safety and efficacydata from two U.S medication namenda. placebo-controlled Phase III clinical trials and an earliertrial conducted among nursing home patients in Europe medication namenda. Phase III data includeda 28-week monotherapy study of 252 patients published earlier this year in theNew England Journal of Medicine and a six-month, 401-patient study of Namendawhen used together with an ongoing regimen of the commonly used Alzheimer'sagent, donepezil medication namenda. In trials, patients treated with Namenda scored higher onmeasures of cognition, daily function, and/or global performance medication namenda. This developmentprogram for memantine was a joint effort between Forest and its licensor, MerzPharmaceuticals, who obtained centralized approval for memantine in the EuropeanUnion in 2002 medication namenda. Merz Pharmaceuticals is a specialty pharmaceutical company dedicatedto research and development in the fields of neurology and psychiatry. In clinical trials, Namenda has been safe and well tolerated medication namenda. The most commonadverse events observed in clinical trials are dizziness, headache, constipation,and confusion medication namenda. Once available in pharmacies, Namenda will be administered orallyat a recommended dose of 10 mg BID following a four-week titration. Alzheimer's is a progressive disease of the brain and it is the most commontype of dementia medication namenda. The term dementia is used to describe the progressive lossof cognitive, intellectual, or functional abilities medication namenda. Published reports projectthat by 2010 more than 5.1 million people in the United States will have Alzheimer'sdisease medication namenda. Currently, all Alzheimer's medications approved in the United Statesbelong to a class of agents called acetylcholinesterase inhibitors, which areindicated for patients with mild to moderate symptoms of the disease medication namenda. Namendais the only approved therapy in the United States for moderate to severe Alzheimer'sdisease.
Namenda (memantine HCl) is the first of a new class of medications for Alzheimer'sdisease with a mechanism of action distinct from currently available drugs medication namenda. Namenda is a low to moderate affinity NMDA (N-methyl-D- aspartate) receptorantagonist medication namenda. It is thought that overexcitation of NMDA receptors by the neurotransmitterglutamate may play a role in Alzheimer's disease since glutamate plays an integralrole in the neural pathways associated with learning and memory medication namenda. The excitotoxicityproduced by abnormal levels of glutamate is thought to be responsible for neuronalcell dysfunction and the eventual cell death observed in Alzheimer's disease medication namenda. Namenda is thought to selectively block the excitotoxic effects associated withabnormal transmission of glutamate, while allowing for the physiological transmissionassociated with normal cell functioning. |
|||
 
|
|||
|
|
|||
|
|
|||
|
|
|||
|
|
|||
|
|
|||
| mmedication namenda meedication namenda meddication namenda mediication namenda mediccation namenda medicaation namenda medicattion namenda medicatiion namenda medicatioon namenda medicationn namenda medication namenda medication nnamenda medication naamenda medication nammenda medication nameenda medication namennda medication namendda medication namendaa edication namenda mdication namenda meication namenda medcation namenda mediation namenda mediction namenda medicaion namenda medicaton namenda medicatin namenda medicatio namenda medicationnamenda medication amenda medication nmenda medication naenda medication namnda medication nameda medication namena medication namend m edication namenda me dication namenda med ication namenda medi cation namenda medic ation namenda medica tion namenda medicat ion namenda medicati on namenda medicatio n namenda medication namenda medication namenda medication n amenda medication na menda medication nam enda medication name nda medication namen da medication namend a medication namenda emdication namenda mdeication namenda meidcation namenda medciation namenda mediaction namenda medictaion namenda medicaiton namenda medicatoin namenda medicatino namenda medicatio nnamenda medicationn amenda medication anmenda medication nmaenda medication naemnda medication namneda medication namedna medication namenad amedication namenda themedication namenda medication namenda | |||
|
|
|||
|
|
|||
|
|
|||
|
Copyright 2005 D-S LTD. |
