|
|
|||
|
|||
|
|
|||
|
alzheimers disease namenda |
|||
|
|
|||
|
|||
 
|
|||
|
|
|||
|
alzheimers disease namenda Generic Name: memantine HCl Date of Approval: Manufacturer: Treatment for: The U.S alzheimers disease namenda. Food and Drug Administration (FDA) has approved Namenda (memantineHCl) for the treatment of moderate to severe Alzheimer's disease alzheimers disease namenda. Namenda isthe first NMDA receptor antagonist to be approved for Alzheimer's disease andis also the only therapy approved for the treatment of moderate to severe Alzheimer'sdisease. Namenda's FDA approval is based on the Agency's review of safety and efficacydata from two U.S alzheimers disease namenda. placebo-controlled Phase III clinical trials and an earliertrial conducted among nursing home patients in Europe alzheimers disease namenda. Phase III data includeda 28-week monotherapy study of 252 patients published earlier this year in theNew England Journal of Medicine and a six-month, 401-patient study of Namendawhen used together with an ongoing regimen of the commonly used Alzheimer'sagent, donepezil alzheimers disease namenda. In trials, patients treated with Namenda scored higher onmeasures of cognition, daily function, and/or global performance alzheimers disease namenda. This developmentprogram for memantine was a joint effort between Forest and its licensor, MerzPharmaceuticals, who obtained centralized approval for memantine in the EuropeanUnion in 2002 alzheimers disease namenda. Merz Pharmaceuticals is a specialty pharmaceutical company dedicatedto research and development in the fields of neurology and psychiatry. In clinical trials, Namenda has been safe and well tolerated alzheimers disease namenda. The most commonadverse events observed in clinical trials are dizziness, headache, constipation,and confusion alzheimers disease namenda. Once available in pharmacies, Namenda will be administered orallyat a recommended dose of 10 mg BID following a four-week titration. Alzheimer's is a progressive disease of the brain and it is the most commontype of dementia alzheimers disease namenda. The term dementia is used to describe the progressive lossof cognitive, intellectual, or functional abilities alzheimers disease namenda. Published reports projectthat by 2010 more than 5.1 million people in the United States will have Alzheimer'sdisease alzheimers disease namenda. Currently, all Alzheimer's medications approved in the United Statesbelong to a class of agents called acetylcholinesterase inhibitors, which areindicated for patients with mild to moderate symptoms of the disease alzheimers disease namenda. Namendais the only approved therapy in the United States for moderate to severe Alzheimer'sdisease.
Namenda (memantine HCl) is the first of a new class of medications for Alzheimer'sdisease with a mechanism of action distinct from currently available drugs alzheimers disease namenda. Namenda is a low to moderate affinity NMDA (N-methyl-D- aspartate) receptorantagonist alzheimers disease namenda. It is thought that overexcitation of NMDA receptors by the neurotransmitterglutamate may play a role in Alzheimer's disease since glutamate plays an integralrole in the neural pathways associated with learning and memory alzheimers disease namenda. The excitotoxicityproduced by abnormal levels of glutamate is thought to be responsible for neuronalcell dysfunction and the eventual cell death observed in Alzheimer's disease alzheimers disease namenda. Namenda is thought to selectively block the excitotoxic effects associated withabnormal transmission of glutamate, while allowing for the physiological transmissionassociated with normal cell functioning. |
|||
 
|
|||
|
|
|||
|
|
|||
|
|
|||
|
|
|||
|
|
|||
| aalzheimers disease namenda allzheimers disease namenda alzzheimers disease namenda alzhheimers disease namenda alzheeimers disease namenda alzheiimers disease namenda alzheimmers disease namenda alzheimeers disease namenda alzheimerrs disease namenda alzheimerss disease namenda alzheimers disease namenda alzheimers ddisease namenda alzheimers diisease namenda alzheimers dissease namenda alzheimers diseease namenda alzheimers diseaase namenda alzheimers diseasse namenda alzheimers diseasee namenda alzheimers disease namenda alzheimers disease nnamenda alzheimers disease naamenda alzheimers disease nammenda alzheimers disease nameenda alzheimers disease namennda alzheimers disease namendda alzheimers disease namendaa lzheimers disease namenda azheimers disease namenda alheimers disease namenda alzeimers disease namenda alzhimers disease namenda alzhemers disease namenda alzheiers disease namenda alzheimrs disease namenda alzheimes disease namenda alzheimer disease namenda alzheimersdisease namenda alzheimers isease namenda alzheimers dsease namenda alzheimers diease namenda alzheimers disase namenda alzheimers disese namenda alzheimers diseae namenda alzheimers diseas namenda alzheimers diseasenamenda alzheimers disease amenda alzheimers disease nmenda alzheimers disease naenda alzheimers disease namnda alzheimers disease nameda alzheimers disease namena alzheimers disease namend a lzheimers disease namenda al zheimers disease namenda alz heimers disease namenda alzh eimers disease namenda alzhe imers disease namenda alzhei mers disease namenda alzheim ers disease namenda alzheime rs disease namenda alzheimer s disease namenda alzheimers disease namenda alzheimers disease namenda alzheimers d isease namenda alzheimers di sease namenda alzheimers dis ease namenda alzheimers dise ase namenda alzheimers disea se namenda alzheimers diseas e namenda alzheimers disease namenda alzheimers disease namenda alzheimers disease n amenda alzheimers disease na menda alzheimers disease nam enda alzheimers disease name nda alzheimers disease namen da alzheimers disease namend a alzheimers disease namenda lazheimers disease namenda azlheimers disease namenda alhzeimers disease namenda alzehimers disease namenda alzhiemers disease namenda alzhemiers disease namenda alzheiemrs disease namenda alzheimres disease namenda alzheimesr disease namenda alzheimer sdisease namenda alzheimersd isease namenda alzheimers idsease namenda alzheimers dsiease namenda alzheimers diesase namenda alzheimers disaese namenda alzheimers disesae namenda alzheimers diseaes namenda alzheimers diseas enamenda alzheimers diseasen amenda alzheimers disease anmenda alzheimers disease nmaenda alzheimers disease naemnda alzheimers disease namneda alzheimers disease namedna alzheimers disease namenad aalzheimers disease namenda thealzheimers disease namenda alzheimers disease namenda | |||
|
|
|||
|
|
|||
|
|
|||
|
Copyright 2005 D-S LTD. |
